Prof. Dr. Nicola Aceto
Prof. Dr. Nicola Aceto
Full Professor at the Department of Biology
Deputy head of Institute of Molecular Health Sciences
- Work phone +41 44 633 82 90
- phone +41 44 633 40 23 Secretariat(Sec.)
- contactsV-Card (vcf, 1kb)
Additional information
Research area
More than 90% of cancer-related deaths are due to the development of a metastatic disease, corresponding to more than 7 million deaths each year worldwide. The Aceto lab is interested in understanding the fundamental molecular mechanisms that drive cancer and its metastatic progression, with a particular focus on the analysis of circulating tumor cells. In our studies, we use a combination of molecular biology, next-generation sequencing, computational biology, microfluidic and robotic technologies, patient samples, in vivo models, genetic engineering, CRISPR screens and drug screens to better understand the biology and vulnerabilities of aggressive cancers. We collaborate actively with a number of academic research groups, hospitals, and healthcare companies throughout the world. Together, we strive to identify novel metastasis-relevant therapeutic opportunities to fight against the metastatic spread of cancer.
Nicola Aceto is Full Professor of Molecular Oncology at the ETH Zurich. Prior to joining ETH, he has been Swiss National Science Foundation Assistant Professor of Oncology at the University of Basel. The Aceto lab contributed to key discoveries in the metastasis field, including investigations of the biology and vulnerabilities of circulating tumor cells and their clusters, some of which already translated into clinical trials for patients with metastatic breast cancer. Nicola completed his training at the Friedrich Miescher Institute (FMI) in Basel, Switzerland, at the Massachusetts General Hospital Cancer Center and Harvard Medical School, and at the Broad Institute of MIT and Harvard in Boston, USA. To date, Nicola received three ERC Grants (StG 2015, PoC 2018, CoG 2020) and numerous awards related to his work on circulating tumor cells, including the Swiss Science Prize Latsis for Groundbreaking Cancer Research, the EACR Translational Cancer Research Award, the Robert Wenner Award from the Swiss Cancer League and the Friedrich Miescher Award for Outstanding Achievements in Biochemistry. He is an inventor in several patent applications related to the diagnosis and treatment of cancer, advisor for several companies with an interest in liquid biopsy, and co-founder of an ETH Spinoff biotech company dedicated to the development of new cancer medicines.
Honours
Year | Distinction |
---|---|
2023 | Robert Wenner Award, Swiss Cancer League |
2023 | The Dr. Ernst Th. Jucker Prize for Research in Molecular Oncology, Zurich, Switzerland |
2023 | The Pezcoller Foundation-EACR Translational Cancer Research Award, European Association for Cancer Research and Pezcoller Foundation |
2022 | EACR Top 10 Cancer Research Publication (Diamantopoulou et al., Nature, 2022), European Association for Cancer Research |
2021 | EACR Top 10 Cancer Research Publication (Gkountela et al., Cell, 2019), European Association for Cancer Research |
2021 | ERC Consolidator Grant |
2021 | Swiss Science Prize Latsis, Swiss National Science Foundation, Bern, Switzerland |
2020 | Friedrich Miescher Award for Outstanding Achievements in Biochemistry |
2019 | ERC Proof-of-Concept Grant |
2019 | Faculty of Medicine Alumni Award for Excellent Scientific Achievements, University of Basel |
2019 | Prize for Scientific Research in the Fight Against Cancer, Vaduz, Liechtenstein |
2016 | ERC Starting Grant |
2016 | Honorable mention, AAAS Wachtel Cancer Research Award, USA |
2016 | Swiss National Science Foundation Professorship |
2013 | Advanced Postdoc Mobility Fellowship, Swiss National Science Foundation |
2013 | Long-Term Fellowship, Human Frontiers Science Program |
2012 | Bruno Speck Award, Basel Stem Cell Network (BSCN), Switzerland |
2012 | Ed Fischer Outstanding Thesis Award, Friedrich Miescher Institute, Switzerland |
2012 | Long-Term Fellowship, European Molecular Biology Organization (EMBO) (respectfully declined) |
2012 | Postdoctoral Fellowship, American-Italian Cancer Foundation, New York, USA (respectfully declined) |
Course Catalogue
Autumn Semester 2024
Number | Unit |
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551-1525-00L | Cancer Progression: Mechanisms, Targets and Therapeutic Approaches |