D-BIOL News Channel (EN)
Stm1 regulates Ifh1 activity revealing crosstalk between ribosome biogenesis and ribosome dormancy
Recent work by the Peter laboratory (IBC) published in "Molecular Cell", in collaboration with the Pilhofer (IMBB, D-BIOL) and Panse (IMM, UZH) groups, and Toulouse and Geneva collaborators demonstrates that the yeast ribosome hibernation factor Stm1 regulates ribosome homeostasis, balancing degradation and biogenesis in different conditions.
Microbial small talk: E. coli and Salmonella fight over the dinner table
A new PLOS Pathogens study by the Hardt (IMB) and Sauer (IMSB) groups shows how chemotaxis, quorum sensing, and metabolism shape E. coli - Salmonella interactions in vivo, affecting mannose use and redox balance at different infection stages.
Understanding how plants grow: The role of OPS/OPL genes
A recent "Journal of Experimental Botany" paper by the Truernit group (IMPB) sheds light on an Arabidopsis gene family crucial for overall plant growth.
Molecular features of substrate recognition in the mycobacterial Bpa-proteasome complex
A new article by the Weber-Ban group, in collaboration with the Glockshuber group and the cryoEM knowledge hub, reveals how the mycobacterial proteasome activator Bpa binds substrates via key ring-lining residues, shedding light on protein degradation in M. tuberculosis.
IL-1 protects from fatal candidiasis by inhibiting oxidative phosphorylation and hypoxia
Systemic candidiasis is a life-threatening infectious disease. A recent study by Horn et al. in the Kopf lab at ETH Zurich reveals different mechanisms by which the multi-functional cytokine IL-1 protects from Candida albicans overgrowth in the kidney and brain.