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A recent Nature Communications paper by the Allain (ETH Zurich), Zavolan (Uni Basel) and Sponer groups identified a novel mode of interaction of the splicing regulator SRSF1 with RNA and found a structure-based mutant that restores the deficient splicing of SMN exon7 responsible for Spinal Muscular Atrophy.

Cytomegalovirus infection induces large numbers of circulating memory CD8 T cells, while influenza virus infection induces tissue-resident memory CD8 T cells in the lung. A recent ‘Mucosal Immunology’ paper by the Oxenius group shows that both subsets equally protect against respiratory infection, albeit employing different mechanisms of activation and relocation.

A recent eLife publication by the Kutay group shows that the inner nuclear membrane protein LAP1 is a novel chromatin-binding factor that fails to be released from mitotic chromatin if the functionality of Torsin ATPases is compromised, inducing chromosome segregation defects and binucleation.

Nicola Aceto took up his position as Associate Professor of Molecular Oncology. This professorship is located in the D-​BIOL's Institute of Molecular Health Sciences.