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ERC Starting Grant for Manuela Hospenthal
In the last application process the European Research Council awarded 11 ERC Starting Grants to ETH researchers. One of the awardees is Manuela Hospenthal, assistant professor in the IMBB. Due to Switzerland's non-association the funds will now be provided by the State Secretariat for Education, Research and Innovation (SERI).
Male and female recombination in diploid Arabidopsis arenosa
A recent paper published in the journal Genetics from the Bomblies lab characterizes the meiotic recombination landscape in male and female meiosis of two diploid Arabidopsis arenosa populations. The study is the first genetic map for this species and thus an important resource, but it also reveals several interesting features.
Ribosomally derived lipopeptides containing distinct fatty acyl moieties
In a recent "PNAS" paper the Piel group (IMB) in collaboration with the Gugger (Institut Pasteur, FR) and Morinaka (National University of Singapore) groups report the first ribosomal peptides with various posttranslational fatty acylations, opening up a synthetic biology route to gene-encoded lipopeptide antibiotics.
Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase
In a recent "Angewandte Chemie International Edition" paper, the Piel group (IMB) in collaboration with the Piechulla group (University of Rostock) report a bacterial polyketide synthase that catalyzes a highly expanded set of biochemical reactions to generate complex bioactive molecules.
Structure of substrate-translocating ATPase-proteasome complex from M. tuberculosis
A recent publication from the Weber-Ban group (IMBB) published in Nature Communications sheds light on Mycobacterium tuberculosis proteasome substrate engagement and translocation, and reveals a previously unknown interaction element between the proteasomal regulator Mpa and the 20S proteasome gate.