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Removal of TREX1 activity enhances CRISPR–Cas9-mediated homologous recombination
A recent “Nature Biotechnology” paper by the Corn group (IMHS) in collaboration with Maciejowski group from Memorial Sloan Kettering Cancer Center identified a novel molecular factor suppressing CRISPR-Cas homology-directed repair.
Non-canonical start codons enhance carbohydrate use in commensal E. coli within the mouse gut
A recent paper in "Nature Microbiology" by the Hardt group (ETH) and the von Mering group (UZH) uncovers a surprising role for non-ATG start codons in boosting lactose utilization in the gut, hinting at a wider impact on nutrient competition and probiotic efficacy.
Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor
A new study published in Cell by the group of Volodymyr Korkhov (IMBB, ETHZ & PSI) in collaboration with the group of Arun Shukla (IIT Kanpur) describes the structure of Duffy antigen receptor for chemokines, DARC.