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Epigenetic and gene expression novelty in polyploids largely reverts during evolution
A recent study from the Bomblies group (IMPB) in Molecular Biology & Evolution investigates chromatin accessibility and transcriptomic changes upon genome duplication as well as subsequent evolution in Arabidopsis arenosa, showing immediate responses to polyploidy can revert during evolution.
Ribosomal peptides with polycyclic isoprenoid moieties
A recent “Chem” paper by the Piel group (IMB) in collaboration with the Chekan (UNC Greensboro) and Gugger groups (Institut Pasteur) reports a new and unusually complex steroid-like post-translational modification.
The hGID GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration
A recent "Life Science Alliance" paper by the Peter group (IBC), in collaboration with the Côté (IRCM, Montréal, Canada) and Pertz groups (ICB, Bern), demonstrates a novel role for the human GID E3 ligase in regulating cell migration by targeting the RhoA-GAP ARHGAP11A for proteasomal degradation.
Nuclear basket regulates the distribution and mobility of nuclear pore complexes in yeast
The Dultz group (IBC) recently published their first paper in MBoC, in collaboration with the Weiss Group (Polytechnique Montréal, Canada), revealing how NPCs show different behaviour in mobility and distribution around the nuclear envelope depending on their composition.