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This work by the Beltrao group recently published in Nature Genetics, describes a network based method to predict novel trait and disease associated genes for more than 1000 human traits. It established relations across the different traits to better understand their biology and explore therapeutic opportunities.

In a collaborative paper in PNAS, Yves Barral with Jorrit Enserink and the Chymkowitch group in Norway shows that the effects on transcription of chromosome condensation during mitosis, is not just a passive phenomenon, but has strong biological significance: It resets the transcriptome to protect cells from uncontrolled transcriptional drift during the following interphase. Thereby, it contributes to the homeostatic control of gene expression regulation.