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In a recent "Nature Communications" article, the Peter group (IBC) reports a modular microfluidic method allowing time-resolved cryo EM sample preparation to visualize biochemical reaction intermediates on sub-second timescales for kinetic and structural characterization.

A recent "EMBO Molecular Medicine" paper by the Werner group (IMHS) in collaboration with the Oxenius group (IMB) demonstrates a novel role of FGFs in the control of viral replication and suggests the use of FGF receptor antagonists for the treatment of viral infections.

Structures of two unique mitoribosomal large subunit assembly intermediates, 28 identified assembly factors, supportive biochemical RNAi knockdowns and more was reported in a recent "Molecular Cell" publication as a result of a fruitful collaboration between the Schneider group at the University of Berne and the Ban lab at ETH Zurich.

Integrator is an essential transcription regulator and RNA processing machinery. It cuts RNA to form the 3'-ends of non-coding RNAs and to terminate production of some mRNAs. Work from the Jonas lab published in "Nature Communications" characterizes the role of a new Integrator module in both processes.

Genomic mutations are associated with a variety of human diseases but their effect on cellular networks remain incompletely understood. A recent “Nature Communications” paper by the Aebersold group shows how cancer-associated genomic mutations modulate the cellular proteome and are translated into molecular phenotypes.